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Conjugated linoleic acid trans-10, cis-12 increases the expression of genes from cell cycle progression and cis-9, trans-11 stimulates apoptotic genes in different mammary tumor explants of female dogs.

E D Da SilvaE C SandriL A FernandesP C CarraroDimas Estrasulas de Oliveira
Published in: Molecular biology reports (2023)
The CLA cis-9, trans-11 stimulates apoptotic genes in mammary tubulopapillary carcinoma, but has a contrary effect on the anaplastic carcinoma, and the CLA trans-10, cis-12 stimulates cell cycle progression genes and may have an antiapoptotic effect, mainly in mammary anaplastic carcinoma.
Keyphrases
  • cell cycle
  • cell proliferation
  • genome wide
  • bioinformatics analysis
  • cell death
  • genome wide identification
  • poor prognosis
  • genome wide analysis
  • anti inflammatory