Cerebellar Volume and Disease Staging in Parkinson's Disease: An ENIGMA-PD Study.
Rebecca KerestesMax A LaansmaConor Owens-WaltonAndrew PerryEva M van HeeseSarah Al-BachariTim J AndersonFrancesca AssognaÍtalo K AventuratoTim D van BalkomHenk W BerendseKevin R E van den BergRebecca BettsRicardo BrioschiJonathan CarrFernando CendesLyles R ClarkJohn C Dalrymple-AlfordMichiel F DirkxJason DruzgalHelena DurrantHedley C A EmsleyGaëtan GarrauxHamied A HaroonRick C G HelmichOdile A van den HeuvelRafael B JoãoMartin E JohanssonSamson G KhachatryanChristine LochnerCorey T McMillanTracy R MelzerPhilip E MosleyBenjamin NewmanPeter OpriessnigLaura Michelle ParkesClelia PellicanoFabrizio PirasToni L PitcherKathleen L PostonMario RangoAnnerine RoosChristian RummelReinhold SchmidtPetra SchwingenschuhLucas S SilvaViktorija SmithLetizia SquarcinaDan J SteinZaruhi TavadyanChih-Chien TsaiDaniela VecchioChris VriendJiun-Jie WangRoland WiestClarissa L YasudaChristina B YoungNeda JahanshadPaul M ThompsonYsbrand D van der WerfIan H Hardingnull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2023)
We provide evidence of a dissociation between anterior "motor" lobe and posterior "non-motor" lobe cerebellar regions in PD. Whereas less severe stages of the disease are associated with larger motor lobe regions, more severe stages of the disease are marked by smaller non-motor regions. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.