Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Liyan SuiYinghua ZhaoWenfang WangHongmiao ChiTian TianPing WuJinlong ZhangYicheng ZhaoZheng-Kai WeiZhijun HouGuoqiang ZhouGuoqing WangZedong WangQuan LiuPublished in: Cell & bioscience (2023)
Our findings reveal the immune evasion mechanisms of flavivirus prM, which may contribute to understanding flavivirus pathogenicity, therapeutic intervention and vaccine development.