Predicting disordered gambling across adolescence and young adulthood from polygenic contributions to Big 5 personality traits in a UK birth cohort.
Kellyn M SpychalaIan R GizerChristal N DavisGenevieve F DashThomas M PiaseckiWendy S SlutskePublished in: Addiction (Abingdon, England) (2021)
Polygenic contributions to low agreeableness and high neuroticism appear to predict two measures of disordered gambling (problem gambling severity index and life-time assessment of DSM-IV pathological gambling symptoms). Polygenic scores for neuroticism interact with age to suggest that the positive association becomes stronger from adolescence through young adulthood.