DECREASED EXPRESSION OF MICRORNA-629 IN GASTRIC CANCER SAMPLES POTENTIATED BY THE VIRULENCE MARKER OF H. PYLORI, CAGA GENE.
Caroline Dos Reis Rodrigues SoaresLucas Matheus Vieira da SilvaBianca Reis AlmeidaJéssica Nunes PereiraMônica Pezenatto Dos SantosSilvana Barbosa SantiagoMarília de Arruda Cardoso SmithSpencer Luiz Marques PayãoLucas Trevizani RasmussenPublished in: Arquivos de gastroenterologia (2024)
H. pylori is a factor involved in the etiology and progression of gastric diseases. Reduction in miRNA-629 expression in cancer patients occurs independent of the presence of the bacterium, but when the cagA pathogenicity marker is present, it induces changes in the gene expression of the respective miRNA.