Vitamin D3 and COVID-19 Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses.

Fausto PetrelliSimone OldaniKaren BorgonovoMary CabidduGiuseppina DogniniMara GhilardiMaria Chiara ParatiDaniela Petro'Lorenzo DottoriniCarmen ReaVeronica LonatiAndrea LucianiAntonio Ghidini

Published in: Antioxidants (Basel, Switzerland) (2023)

This umbrella review of the available evidence suggests that insufficient vitamin D3 may increase COVID-19 infection risk, severity, and mortality, in addition to showing a highly suggestive association between vitamin D3 supplementation and reduced severity and mortality among infected patients.

Keyphrases

meta analyses
systematic review
randomized controlled trial
cardiovascular events
coronavirus disease
sars cov
risk factors
adipose tissue
skeletal muscle
insulin resistance