Beta-blocker effect on ST-segment: a prespecified analysis of the EARLY-BAMI randomised trial.
Enrico FabrisRenicus HermanidesVincent RoolvinkBorja IbanezJan Paul OttervangerGonzalo PizarroNiels van RoyenAlonso Mateos-RodriguezJan Henk DambrinkAgustin AlbarranFrancisco Fernández-AvilésJavier BotasWouter RemkesVictoria Hernandez-JarasElvin KedhiJose ZamoranoFernando AlfonsoAlberto García-LledóMaarten van LeeuwenRobin NijveldtSonja PostmaEvelien KolkmanMarcel GosselinkBart de SmetSaman RasoulErik LipsicJan J PiekValentin FusterArnoud Wj van 't HofPublished in: Open heart (2021)
In patients with STEMI, who were being transported for primary PCI, early IV BB administration did not significantly affect ST-segment deviation after pPCI compared with placebo. The neutral result of early IV BB administration on an early marker of pharmacological effect is consistent with the absence of subsequent improvement of clinical outcomes.