A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA.

Pei LuJie YangMao LiShanshan WenTianzhe ZhangChenchao YanRan LiuYu XiaoXinghuan WangWei Jiang

Published in: Genome biology (2023)

These data suggest that desert lncRNA HIDEN facilitates the interaction between IMP1 and FZD5 mRNA, stabilizing FZD5 mRNA which activates WNT signaling and promotes human definitive endoderm differentiation.

Keyphrases

endothelial cells
binding protein
induced pluripotent stem cells
long non coding rna
pluripotent stem cells
squamous cell carcinoma
electronic health record
radiation therapy
embryonic stem cells
locally advanced
artificial intelligence