High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy.

Rong FanSiru ZhaoJunqi NiuHong MaQing XieSong YangJianping XieXiaoguang DouJia ShangHuiying RaoQi XiaYali LiuYongfeng YangHongbo GaoAimin SunXieer LiangXueru YinYongfang JiangYanyan YuJian SunNikolai V NaoumovJin-Lin Hounull null

Published in: Gut (2024)

The novel GOLDEN model, based on longitudinal qHBsAg data, accurately predicts HBsAg clearance, provides reliable estimates of functional hepatitis B virus (HBV) cure and may have the potential to stratify different subsets of patients for novel anti-HBV therapies.

Keyphrases

hepatitis b virus
liver failure
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
cross sectional
peritoneal dialysis
big data
peripheral blood
bone marrow
deep learning