Liposomal Bupivacaine Single-Injection Compared With Continuous Local Anesthetic Nerve Blocks for Painful Surgeries: A Meta-Analysis of Randomized Controlled Trials and Trial Sequential Analysis.

Lue LiuZhiyong YangKaizhi LuBin YiYong Yang

Published in: Pain practice : the official journal of World Institute of Pain (2020)

This meta-analysis showed that LB single-injection and CNBs have similar efficacy of pain relief and safety in patients after painful surgeries when concomitant with multimodal analgesia. However, the results of TSA indicate that further trials are still needed to confirm these findings.

Keyphrases

pain management
systematic review
ultrasound guided
end stage renal disease
ejection fraction
postoperative pain
chronic pain
newly diagnosed
clinical trial
study protocol
randomized controlled trial
neuropathic pain
phase iii
phase ii
patient reported outcomes
spinal cord
open label
patient reported