Chemo-Preventive Action of Resveratrol: Suppression of p53-A Molecular Targeting Approach.
Rokeya AkterMd Habibur RahmanDeepak KaushikVineet MittalDiana UivarosanAurelia Cristina NechiforTapan BehlChenmala KarthikaManuela StoicescuMihai Alexandru MunteanuCristiana BusteaSimona Gabriela BungauPublished in: Molecules (Basel, Switzerland) (2021)
Extensive experimental, clinical, and epidemiological evidence has explained and proven that products of natural origin are significantly important in preventing and/or ameliorating various disorders, including different types of cancer that researchers are extremely focused on. Among these studies on natural active substances, one can distinguish the emphasis on resveratrol and its properties, especially the potential anticancer role. Resveratrol is a natural product proven for its therapeutic activity, with remarkable anti-inflammatory properties. Various other benefits/actions have also been reported, such as cardioprotective, anti-ageing, antioxidant, etc. and its rapid digestion/absorption as well. This review aims to collect and present the latest published studies on resveratrol and its impact on cancer prevention, molecular signals (especially p53 protein participation), and its therapeutic prospects. The most recent information regarding the healing action of resveratrol is presented and concentrated to create an updated database focused on this topic presented above.
Keyphrases
- anti inflammatory
- papillary thyroid
- squamous cell
- cancer therapy
- emergency department
- physical activity
- healthcare
- drug delivery
- radiation therapy
- squamous cell carcinoma
- young adults
- single molecule
- randomized controlled trial
- current status
- locally advanced
- drinking water
- rectal cancer
- climate change
- protein protein
- human health