Tolerability and efficacy of two doses of aerosolized albuterol in ventilated infants with BPD: A randomized controlled crossover trial.

Natalie NapolitanoKevin DysartLeane SoorikianHuayan ZhangHoward PanitchErik Jensen

Published in: Pediatric pulmonology (2020)

Albuterol at 1.25 mg and 2.5 mg, compared to aerosolized saline, did not affect EF75 in infants with sBPD receiving invasive ventilation. Greater improvement in peak inspiratory pressures with albuterol 2.5 mg suggests benefit, but close heart monitoring may be indicated.

Keyphrases

open label
phase iii
intensive care unit
study protocol
clinical trial
phase ii
double blind
heart failure
placebo controlled
acute respiratory distress syndrome
randomized controlled trial
mechanical ventilation