Near-infrared in vivo imaging system for dynamic visualization of lung-colonizing bacteria in mouse pneumonia.

Daiki YamaguchiGo KamoshidaSyun KawakuboSaki AzumaTakamitsu TsujiNobuo KitadaRyohei Saito-MoriyaNoriteru YamadaRentaro TanakaAyane OkudaKeisuke UeyamaShingo IsakaManaha TomitaRyuichi NakanoYuji MoritaHisakazu YanoShojiro A MakiKinnosuke YahiroShinichi Kato

Published in: Microbiology spectrum (2024)

pulmonary bacterial quantification system utilizing near-infrared luminescence, plasmid-mediated expression of firefly luciferase in bacteria, and a scientific complementary metal-oxide semiconductor camera. Our research holds promise as a useful tool for assessing the efficacy of therapeutic drugs and pathogenesis of infectious diseases.

Keyphrases

infectious diseases
poor prognosis
escherichia coli
high resolution
pulmonary hypertension
crispr cas
quantum dots
high speed
binding protein
convolutional neural network
energy transfer
intensive care unit
drug induced
acute respiratory distress syndrome
community acquired pneumonia
electron microscopy