Long-term kinetics of Zika virus RNA and antibodies in body fluids of a vasectomized traveller returning from Martinique: a case report.
Guenter FroeschlKristina HuberFrank von SonnenburgHans-Dieter NothdurftGisela BretzelMichael HoelscherLothar ZoellerMatthias TrottmannFrancisco Pan-MontojoGerhard DoblerSilke WoelfelPublished in: BMC infectious diseases (2017)
The case presentation adds to the still limited knowledge of kinetics of detection of ZIKV by direct as well as indirect methods. Here, a complete data set including results from PCR, serology and cell culture is provided allowing an improved evaluation of optimum diagnostic periods for testing a variety of sample types. Moreover, a high viral load of ZIKV RNA was detected in ejaculate of the vasectomized patient. This finding sheds new light on the possible localizations of ZIKV replication in the human male reproductive tract.