Biological Age, Chronological Age and Survival in Pulmonary Fibrosis: A Causal Mediation Analysis.
Janelle Vu PugashettiJohn S KimSwaraj BoseAyodeji AdegunsoyeAngela L LinderholmChing-Hsien ChenMary E StrekKevin R FlahertySusan MurrayChad A NewtonShehabaldin AlqalyoobiShwu-Fan MaJosyf C MychaleckyjRussell P BowlerMeiLan K HanJeffrey L CurtisFernando J MartinezJennifer A SmithImre NothJustin M OldhamPublished in: American journal of respiratory and critical care medicine (2024)
Molecular measures of aging completely mediate the relationship between chronological age and survival, suggesting that chronological age has no direct effect on ILD survival.