Human immunotypes impose selection on viral genotypes through viral epitope specificity.

Migle GabrielaiteMarc BennedbækAdrian G ZuccoChristina EkenbergDaniel D MurrayVirginia L KanGiota TouloumiLinos VandekerckhoveDan TurnerJames NeatonH Clifford LaneSandra SafoAlejandro Arenas-PintoMark N PolizzottoHuldrych F GünthardJens D LundgrenRasmus L Marvignull null

Published in: The Journal of infectious diseases (2021)

Our results show the importance of immunotype specificity on viral antigenic determinants, and the identified genetic interplay puts emphasis that viral and human genetics should be studied in the context of each other.

Keyphrases

sars cov
endothelial cells
pluripotent stem cells
gene expression
genome wide
copy number
structural basis
dna methylation
monoclonal antibody