Safety and Activity of PolyPEPI1018 Combined with Maintenance Therapy in Metastatic Colorectal Cancer: an Open-Label, Multicenter, Phase Ib Study.
Joleen M HubbardEnikő R TőkeRoberto MorettoRondell P GrahamHagop YoussoufianOrsolya LőrinczLevente MolnárZsolt CsiszovszkiJessica L MitchellJaclynn WesslingJózsef TóthChiara CremoliniPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
PolyPEPI1018 added to maintenance chemotherapy for patients with unresectable, MSS mCRC was safe and associated with specific immune responses and antitumor activity warranting further confirmation in a randomized, controlled setting.