Efficacy and Safety of Erenumab, Galcanezumab, and Fremanezumab in the Treatment of Drug-Resistant Chronic Migraine: Experience in Real Clinical Practice.

Lorenzo CantarelliDiana Pestana GrafiñaAmanda Gonzalez PerezSara García GilFernando Gutiérrez NicolásEmma Ramos SantanaMarco Antonio Navarro DávilaSheila María Otazo PérezGloria Calzado GómezSergio Perez ReyesGloria Julia Nazco Casariego

Published in: The Annals of pharmacotherapy (2022)

The results confirm the effectiveness and safety of anticalcitonin gene-related peptide (CGRP) drugs in real clinical practice. However, the study shows little benefit from erenumab intensification, with similar effectiveness and worse tolerability than the standard dose.

Keyphrases

drug resistant
clinical practice
multidrug resistant
acinetobacter baumannii
randomized controlled trial
systematic review
open label
genome wide
copy number
gene expression
dna methylation
cystic fibrosis
pseudomonas aeruginosa
study protocol
placebo controlled