Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex.
Anthony P CarnicelliHwanhee HongStuart J ConnollyJohn EikelboomRobert P GiuglianoDavid A MorrowManesh R PatelLars WallentinJohn H AlexanderMaria Cecilia BahitAlexander P BenzErin A BohulaTze-Fan ChaoLeanne DyalMichael D EzekowitzKeith A A FoxBaris GencerJonathan L HalperinZiad HijaziStefan H HohnloserKaiyuan HuaElaine HylekEri Toda KatoJulia KuderRenato Deláscio LopesKenneth W MahaffeyJonas OldgrenJonathan P PicciniChristian T RuffJan SteffelDaniel WojdylaChristopher B Grangernull nullPublished in: Circulation (2022)
Compared with warfarin, DOACs have more favorable efficacy and safety profiles among patients with atrial fibrillation.