Dupilumab in Children with Uncontrolled Moderate-to-Severe Asthma.
Leonard B BacharierJorge F MasperoConstance H KatelarisAlessandro Giovanni FiocchiRemi GagnonInes de MirNeal JainLawrence D SherXuezhou MaoDongfang LiuYi ZhangAsif H KhanUpender KapoorFaisal A KhokharPaul J RoweYamo DenizMarcella RuddyElizabeth LawsNaimish PatelDavid M WeinreichGeorge D YancopoulosNikhil AminLeda P MannentDavid J LedererMegan Hardinnull nullPublished in: The New England journal of medicine (2021)
Among children with uncontrolled moderate-to-severe asthma, those who received add-on dupilumab had fewer asthma exacerbations and better lung function and asthma control than those who received placebo. (Funded by Sanofi and Regeneron Pharmaceuticals; Liberty Asthma VOYAGE ClinicalTrials.gov number, NCT02948959.).