STAT3 Expression and Activity are Up-Regulated in Diffuse Large B Cell Lymphoma of Dogs.

A L F V AssumpçãoP C JarkC C HongZ LuH M RuettenC M HeatonM E PinkertonXuan Pan

Published in: Journal of veterinary internal medicine (2017)

Compared with the normal canine lymph node, DLBCL of dogs has up-regulated STAT3 pathway. Our results support future investigation of JAK inhibitors in the treatment of DLBCL in dogs.

Keyphrases

diffuse large b cell lymphoma
lymph node
epstein barr virus
cell proliferation
transcription factor
poor prognosis
neoadjuvant chemotherapy
binding protein
early stage
sentinel lymph node
smoking cessation