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CSF β-Amyloid and Tau Biomarker Changes in Veterans With Mild Traumatic Brain Injury.

Ge LiJeffrey IliffJane ShoferCynthia L MayerJames S MeabonDavid CookKathleen F PagulayanMurray A RaskindHenrik ZetterbergKaj BlennowElaine R Peskind
Published in: Neurology (2024)
CSF Aβ levels decreased in middle-aged veterans with blast-related mTBI. These data suggest that chronic neuropathologic processes associated with blast mTBI share properties in common with pathogenic processes known to portend AD onset, thus raising concern that veterans with blast-related mTBI may develop a dementing disorder later in life.
Keyphrases
  • mild traumatic brain injury
  • middle aged
  • cerebrospinal fluid
  • machine learning
  • drug induced