Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis.

Tatiana L FonsecaGustavo W FernandesBarbara M L C BoccoAli KeshavarzianShriram JakateTerrence M DonohueBalázs GerebenAntonio Carlos Bianco

Published in: Alcoholism, clinical and experimental research (2019)

EtOH consumption elevates expression of Zfp125. Alb-D2KO animals, which have lower levels of Zfp125, are much less susceptible to EtOH-induced liver steatosis.

Keyphrases

insulin resistance
high fat diet
poor prognosis
high fat diet induced
high glucose
diabetic rats
adipose tissue
metabolic syndrome
binding protein
liver injury
type diabetes
skeletal muscle
oxidative stress