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MR-based proton density fat fraction (PDFF) of the vertebral bone marrow differentiates between patients with and without osteoporotic vertebral fractures.

Florian Tilman GassertA KufnerF G GassertY LeonhardtS KronthalerB J SchwaigerC BoehmM R MakowskiJ S KirschkeT BaumD C KarampinosA S Gersing
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)
MR-based PDFF enables the differentiation between osteoporotic/osteopenic patients with and without vertebral fractures, suggesting the use of PDFF as a potential biomarker for bone fragility.
Keyphrases
  • bone mineral density
  • postmenopausal women
  • bone marrow
  • body composition
  • contrast enhanced
  • magnetic resonance
  • mesenchymal stem cells
  • adipose tissue
  • magnetic resonance imaging
  • fatty acid
  • soft tissue
  • hip fracture