Detection and genome characterization of Middelburg virus strains isolated from CSF and whole blood samples of humans with neurological manifestations in South Africa.
Isabel FourieJune WilliamsArshad IsmailPetrus Jansen van VurenAnton StoltzMarietjie VenterPublished in: PLoS neglected tropical diseases (2022)
Detection of MIDV in CSF of patients with neurological manifestations suggests that the virus should be investigated as a human pathogen with the potential of causing or contributing to neurological signs in children and adults.
Keyphrases
- south africa
- loop mediated isothermal amplification
- endothelial cells
- real time pcr
- label free
- escherichia coli
- young adults
- cerebral ischemia
- induced pluripotent stem cells
- gene expression
- genome wide
- cerebrospinal fluid
- risk assessment
- brain injury
- human health
- sensitive detection
- men who have sex with men
- quantum dots