Axonal abnormalities in vanishing white matter.
Melanie D KlokMarianna BugianiSharon I de VriesWouter GerritsenMarjolein BreurSophie van der SluisVivi M HeineMaarten H P KoleWia BaronMarjo S van der KnaapPublished in: Annals of clinical and translational neurology (2018)
In vanishing white matter, axons are initially normal and atrophy later. Astrocytes are central in this process. If therapy becomes available, axonal pathology may be prevented with early intervention.