Regular use of proton pump inhibitor and risk of rheumatoid arthritis in women: a prospective cohort study.

Jinqiu YuanChanghua ZhangJeffrey A SparksSusan MalspeisKelvin Kam-Fai TsoiJean H KimBenjamin A FisherFang GaoTim SumerlinYan LiuYuxing LiuYihang PanYulong HeJoseph J Y Sung

Published in: Alimentary pharmacology & therapeutics (2020)

Regular use of PPI was associated with increased risk of RA in women, with a higher risk observed in individuals with a longer duration of PPI use. Due to the observational study design, large prospective trials are still required to confirm our finding.

Keyphrases

rheumatoid arthritis
protein protein
disease activity
polycystic ovary syndrome
ankylosing spondylitis
interstitial lung disease
breast cancer risk
small molecule
pregnancy outcomes
cross sectional
cervical cancer screening
adipose tissue
skeletal muscle
insulin resistance
idiopathic pulmonary fibrosis