Orthopedic infections due to Trichosporon species: Case series and literature review.
Andrés Mello LópezLuiz Alves da Silva NetoVítor Falcão de OliveiraVladimir Cordeiro de CarvalhoPriscila Rosalba Domingos de OliveiraAna Lúcia Lei Munhoz LimaPublished in: Medical mycology (2023)
Reports of orthopedic fungal infections caused by Trichosporon species are extremely scarce, thus we aimed to describe a case series and review the cases published in the literature. Patients were retrospectively included if a previous culture of bone, joint, or soft tissues had resulted positive for Trichosporon species along with a clinical diagnosis of an orthopedic infection. Eight patients were included with diverse orthopedic conditions, most of them cases of osteomyelitis. The main isolated species was Trichosporon asahii. All patients were treated with antifungals, mainly voriconazole, and surgical management, resulting in high rates of clinical improvement and low associated mortality.