Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review.

Fulvio CelsiFrancesca PeriJulia CavasinLuisa Zupin Giorgio CozziEgidio BarbiSergio Crovella

Published in: Genes (2023)

Despite the high variability observed in the different studies analyzed, our results suggest that hypermethylation and increased pain sensitivity could be connected, possibly due to the variation of TRPA1 expression.

Keyphrases

chronic pain
poor prognosis
pain management
binding protein
dna methylation
case control
cerebral ischemia
human health
gene expression
risk assessment
blood brain barrier
neuropathic pain