Clinical features and therapeutic responses to proton pump inhibitor in patients with severe reflux esophagitis: A multicenter prospective observational study.

Kimio IsshiNobuyuki MatsuhashiTakashi JohKazuhide HiguchiKatsuhiko IwakiriTakeshi KamiyaNoriaki ManabeTatsuya NakadaMaiko OgawaSeiji ArihiroKen HarumaKoji Nakada

Published in: JGH open : an open access journal of gastroenterology and hepatology (2020)

Sufficient strength and period of PPI therapy are required, even if the symptoms show early improvement, when treating GERD patients without performing endoscopy, considering the possibility of severe ERD.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
early onset
prognostic factors
stem cells
patient reported outcomes
bone marrow
cross sectional
depressive symptoms
small molecule
sleep quality
mesenchymal stem cells
patient reported
double blind