Login / Signup

Bioinformatics approach combined with experimental verification reveals OAS3 gene implicated in paclitaxel resistance in head and neck cancer.

Hasan Onur CaglarAbdulmelik AytatliNeslisah BarlakElanur Aydin KaratasArzu TatarAbdulkadir SahinOmer Faruk Karatas
Published in: Head & neck (2024)
The therapeutic targeting of OAS3 may resensitize PTX-resistant HNSCC cells with high OAS3 expression to PTX treatment.
Keyphrases
  • induced apoptosis
  • poor prognosis
  • cell cycle arrest
  • genome wide
  • cancer therapy
  • copy number
  • endoplasmic reticulum stress
  • combination therapy
  • gene expression
  • pi k akt