Preoperative Amlodipine Is Efficacious in Preventing Intraoperative HDI in Pheochromocytoma: Pilot RCT.
Sanjeet Kumar JaiswalSaba Samad MemonAnurag Ranjan LilaVijaya SarathiManjunath GoroshiRobin GargRohit BarnabasIndrani HemantkumarRajendra D PatelShrikanta OakAbhay DalviMahadeo GaraleVirendra PatilNalini S ShahTushar R BandgarPublished in: The Journal of clinical endocrinology and metabolism (2021)
Preoperative blockade with amlodipine is an efficacious alternative to prazosin GITS in preventing intraoperative HDI in PPGL. Larger studies that compare preoperative blockade by amlodipine with other α-blockers like phenoxybenzamine and/or doxazosin in PPGL patients are warranted.