An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial-an update to the published protocol.

Rindra Vatosoa RandremananaMihaja RaberahonaMamy Jean de Dieu RandriaJosephine BournerGabriella ZadonirinaHanitra RazananaivoThéodora Mayouya-GamanaReziky MangahasimbolaElise PesonelAnnelies GillesenMinoarisoa RajerisonVoahangy AndrianaivoarimananaTansy EdwardsPeter HorbyPiero Olliaro

Published in: Trials (2024)

This article reports an update to the protocol of the IMASOY trial, which was prospectively registered on clinicaltrials.gov (NCT04110340) in October 2019.

Keyphrases

phase iii
pseudomonas aeruginosa
phase ii
open label
study protocol
clinical trial
randomized controlled trial
double blind
placebo controlled
cystic fibrosis
acinetobacter baumannii
emergency department
combination therapy
drug induced