The Function of extravascular coagulation factor IX in haemostasis.
David M MannKatherine A StaffordMan-Chiu PoonDavide MatinoDarrel W StaffordPublished in: Haemophilia : the official journal of the World Federation of Hemophilia (2021)
Preclinical and clinical results support the interpretation that FIX plays a role in haemostasis from its extravascular location. We believe that knowing the CRM status of haemophilia B patients is important for optimizing prophylactic dosing with less trial and error, thereby decreasing clinical morbidity.