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Topical pain control for corneal abrasions: A systematic review and meta-analysis.

Caberry W YuAbirami KirubarajanMatthew YauDawn ArmstrongDavin E Johnson
Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2021)
There was strong evidence to support that topical NSAIDs reduce pain associated with corneal abrasions in the first 48 hours and the need for oral analgesia. The existing evidence was insufficient to support or refute the use of topical anesthetics, cycloplegics, steroids, or BCL for pain control in corneal abrasions. Pressure patching was ineffective at pain reduction and may increase the risk of complications. Delays in healing or other complications were not significantly different between any intervention or control for simple, uncomplicated corneal abrasions; however, larger RCTs are required to identify any differences in rare complications.
Keyphrases
  • chronic pain
  • wound healing
  • pain management
  • neuropathic pain
  • optical coherence tomography
  • risk factors
  • randomized controlled trial
  • cataract surgery