Slight temperature changes cause rapid transcriptomic responses in Trypanosoma cruzi metacyclic trypomastigotes.

Lissa Cruz-SaavedraMarina MuñozLuz Helena PatiñoGustavo A VallejoFelipe GuhlJuan David Ramírez

Published in: Parasites & vectors (2020)

Slight temperature shifts lead to increased cell death of metacyclic trypomastigotes because of the deregulation of gene expression of different processes essential for the TcI and TcII DTUs of T. cruzi.

Keyphrases

trypanosoma cruzi
gene expression
cell death
dna methylation
single cell
cell cycle arrest
cell proliferation
signaling pathway
pi k akt