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Slight temperature changes cause rapid transcriptomic responses in Trypanosoma cruzi metacyclic trypomastigotes.

Lissa Cruz-SaavedraMarina MuñozLuz Helena PatiñoGustavo A VallejoFelipe GuhlJuan David Ramírez
Published in: Parasites & vectors (2020)
Slight temperature shifts lead to increased cell death of metacyclic trypomastigotes because of the deregulation of gene expression of different processes essential for the TcI and TcII DTUs of T. cruzi.
Keyphrases
  • trypanosoma cruzi
  • gene expression
  • cell death
  • dna methylation
  • single cell
  • cell cycle arrest
  • cell proliferation
  • signaling pathway
  • pi k akt