Intra-cavity stem cell therapy inhibits tumor progression in a novel murine model of medulloblastoma surgical resection.
Onyinyechukwu OkolieDavid M IrvinJuli R BagoKevin SheetsAndrew SatterleeAbigail G Carey-EwendVivien LettryRaluca DumitruScott EltonMatthew G EwendC Ryan MillerShawn D HingtgenPublished in: PloS one (2018)
We report a novel image-guided model of MB resection/recurrence and provide new evidence of cytotoxic NSCs/iNSCs delivered into the surgical cavity effectively target residual MB foci.