Antibody responses and risk factors associated with impaired immunological outcomes following two doses of BNT162b2 COVID-19 vaccination in patients with chronic pulmonary diseases.
Zitta Barrella HarboeSebastian Rask HammLaura Pérez-AlósPradeesh SivapalanHelene PrieméTorgny WilckePeter KjeldgaardSaher ShakerAlexander Svorre JordanDina Leth MøllerLine Dam HeftdalJohannes Roth MadsenRafael Bayarri-OlmosCecilie Bo HansenMia Marie Pries-HejeRasmus Bo HasselbalchKamille FoghJose Juan Almagro ArmenterosLinda M HilstedErik SørensenBirgitte LindegaardAndrea BrowatzkiTor Biering-SorensenRuth Frikke-SchmidtSisse Rye OstrowskiKasper Karmark IversenHenning BundgaardSusanne Dam NielsenPeter GarredJens-Ulrik Stæhr JensenPublished in: BMJ open respiratory research (2022)
Patients with chronic pulmonary diseases established functional humoral responses to vaccination, however lower than controls. Age, comorbidities and immunosuppression were associated with poor immunological responses.