Fenfluramine HCl (Fintepla® ) provides long-term clinically meaningful reduction in seizure frequency: Analysis of an ongoing open-label extension study.
Joseph SullivanIngrid E SchefferLieven LagaeRima NabboutMilka PringsheimDinesh TalwarTilman PolsterBradley S GalerMichael LockAnupam AgarwalArnold R GammaitoniGlenn MorrisonGail FarfelPublished in: Epilepsia (2020)
Study results demonstrate that fenfluramine provides clinically meaningful (≥50%) seizure frequency reduction over an extended period in patients with Dravet syndrome. No patient developed VHD or PAH, and fenfluramine was generally well tolerated.