Coexistence of calcified- and lipid-containing plaque components and their association with incidental rupture points in acute coronary syndrome-causing culprit lesions: results from the prospective OPTICO-ACS study.
Youssef S AbdelwahedGregor NellesClara FrickClaudio SeppeltDenitsa MetevaBarbara E StähliHimanshu RaiMatthias RiedelCarsten SkurkUrsula Rauch-KröhnertArash HaghikiaDavid SinningHenryk DregerFabian KnebelTobias TrippelMaximillian KrisperJens KlotscheMichael JonerUlf LandmesserDavid Manuel LeistnerPublished in: European heart journal. Cardiovascular Imaging (2022)
Calcified- and lipid-containing components characterize ruptured fibrous cap ACS-causing culprit lesions. Their coexistence is accelerated directly at the ruptured point, suggesting a pathophysiological contribution in the development of RFC-ACS.