Long-term effectiveness and drug survival of golimumab in patients affected by psoriatic arthritis with cutaneous involvement.
Maria Sole ChimentiPaola ConigliaroFrancesco CasoLuisa CostaAugusta OrtolanPaola TriggianeseMarco TassoGiulia Lavinia FontiMaria Grazia LorenzinRoberto PerriconeRoberta RamondaPublished in: Clinical rheumatology (2021)
A 48-month GLM high drug persistence of PsA patients was observed in real-life, in patients presenting high disease activity, elevated prevalence of comorbidities, and more than one line of treatment at baseline. Patients' characteristics as gender, smoke, BMI, different lines of treatment, and concomitant methotrexate treatment affected treatment persistence, making GLM effective and safe in moderate-severe PsA in a long-term real-life setting. Key Points • Golimumab was effective in psoriatic arthritis, including both musculoskeletal and cutaneous manifestations. • Golimumab effectiveness and drug survival were not affected by comorbidities and patient-related characteristics. • The 4-year drug survival curves confirm the efficacy and safety of golimumab in psoriatic arthritis patients in a real-life setting.