Effect of Positive Airway Pressure on Cardiovascular Outcomes in Coronary Artery Disease Patients with Nonsleepy Obstructive Sleep Apnea. The RICCADSA Randomized Controlled Trial.
Yüksel PekerHelena GlantzChristine Zu EulenburgKarl WegscheiderJohan HerlitzErik ThunströmPublished in: American journal of respiratory and critical care medicine (2017)
Routine prescription of CPAP to patients with CAD with nonsleepy OSA did not significantly reduce long-term adverse cardiovascular outcomes in the intention-to-treat population. There was a significant reduction after adjustment for baseline comorbidities and compliance with the treatment. Clinical trial registered with www.clinicaltrials.gov (NCT 00519597).
Keyphrases
- positive airway pressure
- obstructive sleep apnea
- coronary artery disease
- randomized controlled trial
- sleep apnea
- clinical trial
- study protocol
- cardiovascular events
- percutaneous coronary intervention
- coronary artery bypass grafting
- clinical practice
- open label
- phase ii
- systematic review
- combination therapy
- cardiovascular disease
- heart failure
- left ventricular
- acute coronary syndrome
- aortic stenosis
- electronic health record