Effectiveness research in oncology with electronic health record data: A retrospective cohort study emulating the PALOMA-2 trial.

David MerolaJessica YoungDeborah SchragKueiyu Joshua LinSarah AlwardtSebastian G Schneeweiss

Published in: Pharmacoepidemiology and drug safety (2022)

Under our assumptions on missing data and comparability of the two study populations, results from our non-randomized study closely matched that of the randomized trial. Further studies are needed to determine whether EHR data can yield reliable conclusions on treatment effects in oncology.

Keyphrases

electronic health record
clinical decision support
palliative care
adverse drug
randomized controlled trial
systematic review
big data
machine learning
phase iii
phase ii
artificial intelligence
data analysis