Smoking Obstructive Sleep Apnea: Arguments for a Distinctive Phenotype and a Personalized Intervention.
Marina Ruxandra OţeleaMihaela TrencheaAgripina RașcuSabina AntoniuCorina Aurelia ZugravuStefan Sebastian BusnatuAnca Angela SimionescuOana Cristina ArghirPublished in: Journal of personalized medicine (2022)
The SOSA phenotype includes younger male patients with a higher waist circumference, suggesting central obesity. They have a higher prevalence of COPD and a greater severity of OSA, in correlation with the number of pack-years of smoking.
Keyphrases
- obstructive sleep apnea
- body mass index
- positive airway pressure
- smoking cessation
- weight gain
- randomized controlled trial
- body weight
- metabolic syndrome
- insulin resistance
- chronic obstructive pulmonary disease
- weight loss
- type diabetes
- risk factors
- sleep apnea
- lung function
- high fat diet induced
- adipose tissue
- cystic fibrosis
- air pollution