Identification of TIA1 mRNA targets during human neuronal development.

Loryn P ByresMarat MufteevKyoko E YukiWei WeiAlina PieknaMichael D Wilson Deivid C Rodrigues James Ellis

Published in: Molecular biology reports (2021)

Our results reveal TIA1 mRNA targets in hESCs and during human neurodevelopment, indicate that translation repression is a key process targeted by TIA1 binding and implicate TIA1 function in neuronal differentiation.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
binding protein
gene expression
cancer therapy
genome wide
drug delivery
single cell
cerebral ischemia
blood brain barrier
dna binding