Benralizumab in severe eosinophilic asthma in real life: confirmed effectiveness and contrasted effect on sputum eosinophilia versus exhaled nitric oxide fraction - PROMISE.
Florence SchleichCatherine MoermansLaurence SeidelCéline KempeneersGilles LouisFlorence RogisterSophie TombuLaurence PottierAnne-Lise M L PoirrierStéphanie ZiantMonique HenketCarole SanchezVirginie PaulusFrançoise GuissardAnne-Françoise DonneauRenaud LouisPublished in: ERJ open research (2023)
In our real-life study, we confirm the results published in randomised controlled trials showing a sharp reduction in exacerbations and oral corticosteroid therapy, an improvement in asthma control and quality of life, and a dramatic reduction in sputum eosinophil count.
Keyphrases
- cystic fibrosis
- chronic obstructive pulmonary disease
- lung function
- nitric oxide
- mycobacterium tuberculosis
- pulmonary tuberculosis
- allergic rhinitis
- randomized controlled trial
- systematic review
- early onset
- hydrogen peroxide
- stem cells
- peripheral blood
- chronic rhinosinusitis
- nitric oxide synthase
- air pollution
- smoking cessation
- replacement therapy