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Which Is More Suitable for First-Line Treatment of Extensive-Stage Small Cell Lung Cancer, PD-L1 Inhibitors Versus PD-1 Inhibitors? A Systematic Review and Network Meta-Analysis.

Wenjing LiuLulin YuYuqian FengSiyu HuangYuxin HuaMingying PengShanming RuanKai Zhang
Published in: The clinical respiratory journal (2024)
In comparison to placebo + chemotherapy, PD-L1 inhibitors + chemotherapy and PD-1 inhibitors + chemotherapy significantly improved survival for ES-SCLC. According to the available data, PD-L1 inhibitors + chemotherapy and PD-1 inhibitors + chemotherapy had equivalent efficacy and safety; however, the level of evidence of this type of comparison is limited.
Keyphrases
  • small cell lung cancer
  • locally advanced
  • squamous cell carcinoma
  • randomized controlled trial
  • radiation therapy
  • deep learning
  • artificial intelligence