Efficacy analysis of hydroxychloroquine therapy in systemic lupus erythematosus: a study on disease activity and immunological biomarkers.
Seyed Mostafa MonzaviAida AlirezaeiZhaleh Shariati-SarabiJalil Tavakol AfshariMahmoud MahmoudiBanafsheh DormaneshFaezeh JahandoostAli Reza KhoshdelAli Etemad RezaiePublished in: Inflammopharmacology (2018)
HCQ therapy is effective on clinical improvement of SLE patients through interfering with inflammatory signaling pathways, reducing anti-DNA autoantibodies and normalizing the complement activity.
Keyphrases
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- end stage renal disease
- rheumatoid arthritis patients
- ankylosing spondylitis
- chronic kidney disease
- signaling pathway
- ejection fraction
- prognostic factors
- oxidative stress
- peritoneal dialysis
- stem cells
- mesenchymal stem cells
- epithelial mesenchymal transition
- single molecule
- cell free
- patient reported outcomes
- circulating tumor cells
- nucleic acid
- endoplasmic reticulum stress