Monocyte Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Expression Correlates with cIMT in Mexican Hypertensive Patients.

Ricardo GamboaMaría José Jaramillo-EstrellaMaría Del Rocio Martínez-AlvaradoMaria Elena SotoYazmin Estela Torres-PazDavid de Gonzalo-CalvoLeonardo Del Valle-MondragónRebeca López-MarureVicenta C Llorente-CortésClaudia Huesca-Gómez

Published in: Arquivos brasileiros de cardiologia (2021)

An increase in cIMT was found in subjects with hypertension, associated with higher mRNA and LRP1 protein expressions in monocytes, irrespective of the presence of dyslipidemias in HT patients. These results suggest that LRP1 upregulation in monocytes from Mexican hypertensive patients could be involved in the increased cIMT. (Arq Bras Cardiol. 2021; 116(1):56-65).

Keyphrases

hypertensive patients
blood pressure
low density lipoprotein
dendritic cells
poor prognosis
binding protein
end stage renal disease
ejection fraction
chronic kidney disease
prognostic factors
cell proliferation
signaling pathway
patient reported outcomes