Molecular signalling involved in upper airway remodelling is enhanced in patients with obstructive sleep apnoea.

Ching-Chi LinY-P WangC-H ChiuY-K SunM-W LinI-S Tzeng

Published in: The Journal of laryngology and otology (2022)

Patients with obstructive sleep apnoea demonstrated more severe inflammation, increased airway remodelling, and increased protein and messenger RNA expression of pro-inflammatory and pro-fibrotic cytokines in the uvula than control participants.

Keyphrases

positive airway pressure
sleep quality
physical activity
poor prognosis
oxidative stress
binding protein
obstructive sleep apnea
systemic sclerosis
early onset
idiopathic pulmonary fibrosis
anti inflammatory
protein protein
sleep apnea
amino acid
small molecule
single molecule
depressive symptoms